Consider the following statements about the phosphorylation…

Biology Respiration in Plants Skill Builder Single Correct MCQ

Published on: August 21, 2026

Consider the following statements about the phosphorylation of glucose in the first step of glycolysis:

Phosphorylation of glucose to glucose-6-phosphate (G6P) is catalyzed by the enzyme hexokinase or glucokinase. , , ,

The phosphorylated glucose molecule can easily exit the cell due to its negative charge. and , and

This step represents an energy investment, consuming ATP. and and only

Phosphorylation at this stage acts as a regulatory mechanism, preventing further glucose uptake when energy levels are high.
Which of the following combinations of statements is correct? only only only

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The correct answer is:

Statement A is true. Hexokinase or glucokinase catalyzes the phosphorylation of glucose.
Statement B is false. The phosphorylation actually traps glucose in the cell because G6P cannot easily cross the cell membrane.
Statement C is true. This step consumes ATP, marking the beginning of the energy investment phase of glycolysis.

Statement D is true. The product of this reaction, G6P, can inhibit hexokinase, thus regulating the glucose uptake based on the cell's energy needs

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